Lowering LDL cholesterol as low as possible may reduce cardiovascular disease death but increase death from diabetes complications, dementia, and cancers.

“the argument that Peter has made is that cardiovascular disease is the number one killer Therefore your main focus for living a long amount of time should be lowering your LDL as low as possible because we know that if you lower your LDL you're less likely to die of cardiovascular disease and that may be true I think that's probably true the lower your LDL the lower your risk of dying from cardiovascular disease but what about your risk of dying from other things complications of diabetes uh dementia cancers uh that there are all sorts of other risks”