Assessing phenotypic markers like hyperinsulinemia and subtle signs of insulin resistance is more valuable than knowing a genetic predisposition to type 2 diabetes.

“does it help me to know that someone has a genetic predisposition to type two diabetes not nearly as much as it helps me to know while they are still non-diabetic that they have hyperinsulinemia and even if they don't have it well fasting to know that they have postprandial hyperinsulinemia it's very important to look at other subtle markers of insulin resistance the elevation of ferret in some of the other things that we see other patterns of glucose disposal these things matter a lot more frankly”