Large and frequent blood sugar spikes negatively impact long-term health, potentially contributing to atherosclerosis risk, diabetes risk, and affecting endothelial function, blood-brain barrier function, and brain cells.

“large spikes and frequent sites and blood sugar can have an impact on on long-term health um you know there are some studies again sort of associational but looking at Mage so mean amplitude of glycemic excursions and a degree of atherosclerosis risk of diabetes um and you know I think there's a signal there we don't understand it perfectly uh but I and but there's also you know some data suggest that you know very large and persistently elevated glucose may affect endothelial function which then you know could start to contribute to the process of atherosclerosis um you know may also affect blood-brain barrier function may you know uh start to affect cells within the brain so I think there's some potential for for an issue there”