Reducing homocysteine levels with B vitamin supplementation (B12 and folate) can slow cognitive decline and brain atrophy.

“he has done a number of Interventional studies looking at this uh the main one is the vitacog study uh where they uh randomized individuals with elevated homocysteine to a B vitamin supplement it was a B12 and folate folic acid um and then looked at rate of cognitive decline and rate of brain atrophy and they showed that if you could reduce homocysteine and the the greatest risk is is with those with the home system above 13 there's also an elevated risk in those with a home system above 11.”