Rhonda Patrick· PhD
you are going to have to significantly raise plasma vitamin C levels over their normal steady state levels
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
you are going to have to significantly raise plasma vitamin C levels over their normal steady state levels
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newer understandings of bioavailability might ultimately inform new trial designs that could still show a stronger effect especially since plasma increases of low-dose vitamin C treatments are both transy and diminished especially in trials that don't establish rigorous frequent dosing schedules