Rhonda Patrick· PhD
Vitamin C is also involved in the production of interferon in mice
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Vitamin C is also involved in the production of interferon in mice
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when vitamin C deficient mice were supplemented with vitamin C prior to viral infection to achieve plasma levels of approximately eighty to a hundred micromoles similar to that of normal mice there was no increase in viral titers in their lungs and the production of antiviral cytokines increased this study showed that supplementation with vitamin C prior to viral infection protected the formerly deficient mice from death
in mouse models in which mice are vitamin C deficient and have increased pro-inflammatory cytokines giving the mice vitamin C normalized cytokine production
a really interesting study using a vitamin c deficient mouse model demonstrated that these mice had increased pro-inflammatory cytokines and a 10 to 15 fold increase in viral titers in their lungs during viral infection compared to normal mice
one week after the mice developed a viral infection all of the vitamin C deficient mice had died but all of the normal mice survived
Vitamin C also appears to boost the immune system by promoting the proliferation of T-cells and preventing T-cell death. T-cells play a major role in driving an immune response against pathogens, such as bacteria or viruses. Vitamin C also participates in the production of interferon in mice. Interferon is a type of cytokine that signals the body to initiate antiviral defenses.