In young mice, turning back cellular age using Yamanaka factors can promote optic nerve regrowth.

“the first thing we do is we crush the optic nerve so you took a normal mouse and you crushed its optic nerve so now it can't see ya and only very very young mice will regrow nerves you break your spine you're not gonna walk again and so we thought maybe if we turn the age of those cells back to being extremely young they'll grow back and there's nothing that works to grow all the way back healthy optic nerve so we did that”

“he puts pressure in the eye pressure is one of the largest rivers of glaucoma and disrupts vision and then third experiment was to take just regular old mice there were two years of age and reprogram those actually there were 12 months of ia tweeting go too far but by 12 months of age Mouse has lost a lot of education about interesting cuz that's only about 35 year-old human right yeah 40 it's about 40 year old but those mice we thought even that's an old house so most people can't restore vision in anything we have now treated much older mice and we do see some partial effects but okay so let me recap that”