Pre-workout caffeine at high doses might limit the muscle performance benefits you'd other

Well SupportedCombining creatine with high-dose caffeine (>= 250 mg) pre-workout may not significantly impact long-term strength gains, but it can diminish acute performance benefits.

Well SupportedCreatine enhances calcium uptake in muscle cells, improving muscle relaxation time and enabling faster, more explosive movements.

Well SupportedCreatine alone shortened muscle relaxation time by 5%, while caffeine alone increased it by 10%.

Partially SupportedThe interference between caffeine and creatine is likely minor, and both substances have positive effects on performance.

Not Supported