Creatine hydrochloride supplementation increased brain creatine levels by 17% in peri/post

Well SupportedCreatine dosage for muscle benefits is typically 5 grams, but can be higher for cognitive benefits or for individuals with larger body mass (0.1g/kg body weight).

Partially SupportedMedium-dose creatine hydrochloride may be an effective intervention to enhance brain creatine and cognitive function in women at a lower dose than creatine monohydrate.

Partially SupportedCreatine hydrochloride at 1.5 grams per day may improve mood and lipid profiles in peri/postmenopausal women.

Partially SupportedCreatine hydrochloride supplementation at 1.5 grams per day increased brain creatine levels by 17% and improved reaction time by ~7% in peri/postmenopausal women.