Vigorous physical activity is at least 8x more effective for cardiovascular disease preven

Partially SupportedShear stress from blood flow improves endothelial function and arterial health.

Partially SupportedVigorous exercise provides an outsized benefit on cardiovascular outcomes in individuals aged 40-79.

Partially SupportedHigh-intensity exercise is superior to lower-intensity exercise for improving endothelial function, reducing artery stiffness, and lowering the risk of major adverse cardiovascular events.

Partially SupportedHigher intensity physical activity more potently stimulates shear stress on the vascular endothelium compared to lower intensities.