A Comprehensive Review of Non-Steroidal Anti-Inflammatory Drug Use in The Elderly.

NSAIDs, non-steroidal anti-inflammatory drugs, are one of the most commonly prescribed pain medications. It is a highly effective drug class for pain and inflammation; however, NSAIDs are known for multiple adverse effects, including gastrointestinal bleeding, cardiovascular side effects, and NSAID induced nephrotoxicity. As our society ages, it is crucial to have comprehensive knowledge of this class of medication in the elderly population. Therefore, we reviewed the pharmacodynamics and pharmacokinetics, current guidelines for NSAIDs use, adverse effect profile, and drug interaction of NSAIDs and commonly used medications in the elderly.

Full text isn't openly available for this paper (Aging Dis is largely paywalled). The abstract above is the grounded summary. Read at source →

Native comments, Twitter mentions, and Reddit threads about this paper — surfaced together so the conversation isn't fragmented across platforms.