The Carnivore Code, Full ketocon 2019 talk.

PS

Paul Saladino47m · 2019-07-25

Claims Made

105

Claims Supported

72

Support Rate

69%

Support rate

72 of 105 claims supported

72 supported33 partial / not

Claims from this content

87

Well SupportedAll vitamins and minerals found in plants can be obtained from animal sources in more bioavailable forms.Well SupportedAn animal-based diet, consisting of organs, grass-fed meat, fruit, honey, and raw dairy, is considered evolutionarily consistent and nutrient-rich.Well SupportedHumans have historically relied on animal foods as the primary source of protein and nutrients.Well SupportedPhytic acid in oats can inhibit the absorption of divalent cations like calcium, iron, and magnesium when consumed with other foods.Well Supported

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A. Volkovreader

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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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N. Park

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Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

Plant-based protein is at least twice less bioavailable than animal protein.

Not SupportedPhytochemicals found in plants are not true nutrients because they do not serve an indispensable or necessary role in the human body, unlike vitamins or minerals.

Well SupportedStudies show resolution of idiopathic constipation when fiber is removed, contradicting the necessity of fiber for bowel movements.

Well SupportedThe majority of pesticides in the American diet are naturally produced by plants for self-defense.

Well SupportedHumans historically prioritized animal foods over plant-based foods when available.

Well SupportedThe carnivore diet may be helpful for individuals with colitis or Crohn's disease.

Well SupportedPaul Saladino's eczema and asthma improved significantly after adopting a carnivore diet, eliminating plant and fungal foods.

Not SupportedThe classification of red meat as a probable carcinogen is based on weak evidence with limited statistically significant associations.

Well SupportedVitamin K2 intake is associated with reduced heart disease mortality, while vitamin K1 intake is not.

Well SupportedVitamin K2 in animal products like eggs, meat, and liver may prevent heart disease by directing calcium deposition.

Well SupportedThe significant increase in human brain size is strongly linked to the consumption of animal foods.

Well SupportedTurmeric is high in oxalates, leading to greater urinary oxalate excretion and absorption compared to cinnamon.

Well SupportedMost chronic illness is inflammatory, and inflammation and autoimmunity are considered synonymous.

Well SupportedIndividuals on carnivore diets often clinically experience resolution of GI inflammation and significant improvements in gas and bloating.

Well SupportedFor individuals without autoimmune or inflammatory issues, a carnivore-ish diet or incorporating plant products can be appropriate for maintaining a high quality of life.

Well SupportedHormesis involves a small amount of cellular damage from stimuli like exercise or cold plunges, which makes the body stronger upon repair.

Not SupportedIncreasing fiber intake is not necessarily required for a healthy microbiome, and decreasing fiber does not automatically lead to an unhealthy microbiome.

Partially SupportedAn animal-based or carnivorous diet is beneficial for human health.

Partially SupportedMicronutrients from animal foods are essential for quality of life and longevity.

Not SupportedHigh oxalate foods such as almonds, spinach, rhubarb, beets, and turmeric powder can cause issues and should be avoided.

Partially SupportedThe speaker's hs-CRP was higher (just over 1) a year prior when following an organic Paleo diet.

Partially SupportedInherent antioxidant defense mechanisms in humans are sufficient to protect circulating mononuclear blood cells from reactive oxygen species.

Partially SupportedA Tier 1 carnivore diet prioritizes animal foods and organ meats, while incorporating well-tolerated plant foods.

Partially SupportedAnimal fat contains unique nutrients that are crucial for human health and may have contributed to the increase in human brain size.

Partially SupportedPlant phytochemicals can act as hormetic stressors by being oxidative stressors, activating the Nrf2 pathway to increase glutathione production.

Partially SupportedPlants have evolved numerous defenses to discourage animals and insects from eating them over millions of years.

Partially SupportedA strict paleolithic diet did not resolve the speaker's eczema.

Partially SupportedConsuming animal foods does not cause cancer or heart disease.

Partially SupportedAnimal foods are at the top of a hierarchy of food quality and nutrient availability.

Partially SupportedLectins are carbohydrate-binding proteins found in plants that can cause problems in humans due to differing biological operating systems.

Partially SupportedThe speaker lost approximately 20 pounds of muscle mass while running extensively and following a raw vegan diet.

Partially SupportedEating nutrients from well-raised animals is a fundamental practice for improving health.

Partially SupportedHuman brains have decreased in size since peaking 10,000-20,000 years ago.

Partially SupportedNutrient bioavailability is critical because unabsorbed nutrients do not provide health benefits.

Partially SupportedRemoving fruits and vegetables from the diet can lead to improved oxidative stress markers.

Partially SupportedApproximately half of 52 natural pesticides tested in high-dose animal cancer tests were found to be rodent carcinogens.

Partially SupportedPlants contain internal chemical defenses, such as oxalates and lectins.

Partially SupportedMaking plants a staple of the diet leads to suboptimal health.

Not SupportedThere is no evidence that phytochemicals have a unique beneficial effect beyond what can be achieved through other means like cold water swimming.

Partially SupportedClinical outcomes are a more valuable indicator of gut microbiome health than species identification.

Partially SupportedFolate from leafy greens is less bioavailable than folate in animal foods.

Partially SupportedFiber is not necessary for normal bowel movements in individuals on a carnivore diet.

Not SupportedThe hypothesis that LDL is a primary driver of cardiovascular issues is greatly overblown.

Not SupportedThe LDL hypothesis is incorrect; LDL is not directly toxic to the endothelium.

Partially SupportedA carnivore diet may resolve autoimmunity.

Not SupportedThe idea that red meat causes heart disease is likely incorrect, as evidenced by inverse associations in some Asian populations.

Partially SupportedConstructing a carnivore diet involves considering fat-to-protein ratio, consuming organ meats, and managing electrolytes.

Partially SupportedElectrolyte balance, particularly sodium, is important to consider for negative effects on a carnivore diet.

Partially SupportedIncreasing vegetable intake in overweight, obese, postmenopausal women leads to a rise in plasma carotenoids but does not modify oxidative stress or inflammation.

Not SupportedPhytochemicals can have negative effects, such as sulforaphane competing with iodine for the thyroid and curcumin potentially damaging DNA.

Not SupportedHumans likely have adequate antioxidant defense without needing sulforaphane, and other substances also activate the Nrf2 pathway.

Not SupportedAssessing gut microbiome health by identifying specific species is overly granular.

Partially SupportedCurcumin affects the herb channel potassium channel, damaging both native and cancerous cells in cell culture.

Not SupportedA 24-day intervention involving either no fruits and vegetables or a daily intake of 1.5 pounds of fruits and vegetables (or equivalent vitamins/minerals in a pill) showed no change in oxidative damage to DNA.

Partially SupportedHaving a high LDL on a carnivorous or ketogenic diet is not a cause for concern.

Partially SupportedOther factors, not LDL, drive the initial stages of plaque formation.

Not SupportedInterventional trials investigating the effects of high vegetable consumption on immunological and antioxidant markers have not shown significant changes in these markers.

Partially SupportedPhytochemicals, cigarette smoke, and smoked meats all activate the same system in the liver.

Limited ResearchVitamin K2 can be used for clotting, suggesting the human diet may not have a unique role for vitamin K1.

Partially SupportedCigarette smoke exposure initially decreases glutathione levels by 50%, which then rebound to three times basal levels within two hours and peak at 16 hours with a six-fold increase.

Partially SupportedEating organs is beneficial due to their nutrient density, including electrolytes.

Not SupportedHumans may not need phytochemicals for optimal antioxidant response due to environmental hormesis.

Partially SupportedPlant B vitamins are less bioavailable than animal B vitamins because they are bound to glycoproteins.

Partially SupportedWhen incorporating plants into a carnivore diet, it is important to be mindful of potential toxins like oxalates and lectins.

Partially SupportedVagotomy was associated with a 40% lower incidence of Parkinson's disease over 20 years in a Danish study.

Partially SupportedHumans evolved as facultative carnivores, and eating animals was likely crucial to human evolution.

Partially SupportedIncorporating animal foods into the diet can lead to significant muscle mass gain.

Partially SupportedPesticides found in cabbage may interrupt DNA synthesis and replication and break chromosomes.

Partially SupportedPolycyclic aromatic hydrocarbons (PAHs) from grilled meats trigger the Nrf2 pathway.

Not SupportedOxalates found in plants may have negative health implications, such as being present in breast tissue and potentially inducing breast cancer or renal inflammation.

Partially SupportedCompounds like resveratrol, pterostilbene, and curcumin are plant defense chemicals.

Not SupportedMolecular hormesis is a misunderstood term and has been incorrectly applied to molecules.

Partially SupportedSome plant chemicals, like those in cabbage, act as pesticides and can damage chromosomes or interrupt DNA synthesis.

Partially SupportedThe Neolithic Revolution led to population expansion and increased calorie access but resulted in a decline in bioavailable micronutrients and increased health problems.

Partially SupportedWild plants in ancestral environments were largely inedible and potentially toxic compared to modern cultivated varieties.

Partially SupportedLectins from beans can be transported from the gut to the brain and may cause lesions resembling Parkinson's disease.

Partially SupportedOxalates can be found in breast tissue and may induce breast cancer.

Partially SupportedPlants have evolved defense mechanisms to prevent consumption.

Partially SupportedModern plants like broccoli and potatoes have been heavily hybridized and are significantly different from their wild ancestral counterparts.

Partially SupportedMany foods, including almonds, are toxic in their wild state and have been hybridized to be edible.

Partially SupportedCalcium oxalate crystals can induce renal inflammation.

Not SupportedMolecular hormesis is often misunderstood and incorrectly applied to molecules, unlike environmental hormesis.

Partially SupportedThe speaker aims to define axioms of an optimal human diet.