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Kick Veggies to the Curb and Go Full Carnivore – Paul Saladino, M.D.

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Paul Saladino1h 22m · 2019-08-28

Support Rate

77%

117 of 152 claims supported

Support rate

117 of 152 claims supported

117 supported35 partial / not

Claims from this content

133

Well SupportedOn a carnivore diet, balance methionine from muscle meat with glycine from connective tissue to avoid biochemical imbalances.Well SupportedGut cells can utilize ketones from circulation, which enter the butyrate metabolic pathway, as butyrate is converted to beta-hydroxybutyrate before energy use.Well SupportedOrganic kale can have higher levels of thallium than non-organic kale.Partially SupportedGut bacteria convert choline and carnitine into TMA, which the liver oxidizes to TMAO, a contributor to atherosclerosis.Well SupportedCholine supplementation has been shown to improve non-alcoholic fatty liver disease, and choline deficiency can cause fatty liver.

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A. Volkovreader

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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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Well SupportedCollagen from animal connective tissue can be fermented into short-chain fatty acids.

Well SupportedThe significant increase in human brain size is strongly linked to the consumption of animal foods.

Well SupportedA study found a positive association between red meat consumption and telomere length.

Not SupportedWestern medicine often errs by addressing symptoms with medications without tackling the fundamental imbalance that caused the illness, leading to future health issues.

Well SupportedAn elimination diet is a tool for identifying how specific foods affect an individual.

Well SupportedPlant-derived lectins can interfere with human biology.

Well SupportedGrass-fed ruminant animals contributing to soil health can increase soil's carbon carrying capacity and decrease overall greenhouse gases.

Well SupportedPlants contain toxins that can cause negative reactions in some individuals due to co-evolution with animals.

Well SupportedCooked liver or desiccated capsules are nutritious alternatives to raw liver.

Well SupportedAlternating between anabolic and catabolic states is a sensible physiological approach for humans.

Not SupportedEpidemiological studies cannot definitively answer questions about the health effects of specific foods like meat.

Partially SupportedElevated TMAO levels from insulin resistance or kidney disease differ from those caused by choline and carnitine intake.

Not SupportedCharring meat can create carcinogenic polyaromatic hydrocarbons, and charred portions should be cut off.

Partially SupportedPeople should avoid charring meat and use strategies to mitigate the formation of polycyclic aromatic hydrocarbons during cooking.

Partially SupportedInsulin resistance may cause higher TMAO levels, rather than TMAO causing negative health outcomes.

Partially SupportedThe risk associated with a marker like TMAO or Lp(a) may stem from its underlying cause, such as insulin resistance or inflammation.

Partially SupportedThe carnivore diet can be considered the ultimate elimination diet.

Partially SupportedCorn sprayed with estrogenic atrazine and moldy grains is often fed to cows.

Partially SupportedA fasting glucose level between 70-80 mg/dL is considered optimal for longevity.

Partially SupportedEating raw duck egg yolks may be preferable to cooked yolks due to partial degradation of some compounds by heat.

Partially SupportedSearing the outside of meat is sufficient to eliminate surface bacteria without significantly heating the interior.

Partially SupportedPlants can trigger insomnia or other negative effects in some individuals.

Partially SupportedConsuming excess methionine without balancing it with glycine may lead to biochemical stress.

Partially SupportedElevated ferritin above 400-500 should be investigated with a GGT test to assess liver oxidative stress.

Partially SupportedPlants contain internal chemical defenses, such as oxalates and lectins.

Partially SupportedA 1:1 ratio of collagen to methionine, tryptophan, and cysteine from muscle meats is recommended for balancing inflammatory and anti-thyroid effects.

Partially SupportedFreezing liver for a period can eliminate pathogens.

Not SupportedHeavy metals in fish can lead to heavy metal toxicity and suboptimal human health.

Partially SupportedInsulin levels will rise postprandially even when consuming fat and meat, preventing a chronically low insulin state.

Partially SupportedRuminant animals increase the quantity and quality of the global food supply without competing with humans for resources.

Partially SupportedPolycyclic aromatic hydrocarbons (PAHs) are formed by cooking meat on the surface and can affect humans.

Not SupportedOvereating muscle meat on a carnivore diet can lead to biochemical stress due to unfavorable methionine and glycine ratios.

Partially SupportedThere is an optimal protein intake range for humans, below which sarcopenia and bone density issues can occur, and above which negative metabolic effects may arise.

Partially SupportedAtrazine has an estrogenic effect that can accumulate in the fat and muscle of animals fed non-grass-fed feed.

Partially SupportedZearanol, used in cattle feed, increases feed efficiency by 30% in cows, suggesting hormone manipulation rather than just calorie balance.

Partially SupportedChronic inflammation and autoimmunity are essentially synonymous and represent a significant health issue in Western medicine.

Partially SupportedThe speaker is eating exclusively raw meat and plans to remeasure oxidative stress markers, F2 isoprostanes, malondialdehyde, and 8-hydroxy-2-deoxyguanosine.

Partially SupportedGreenhouse gas emissions from grass-fed ruminant animals are minuscule compared to those from technology and burning fossil fuels.

Partially SupportedThe speaker prefers steaks rare to mid-rare to minimize heating the interior.

Partially SupportedProperly raised and cooked pork belly can provide sustained well-being and energy for several hours.

Partially SupportedMethods to reduce oxalic acid in kale include specific cooking techniques, binding agents, and choosing lower oxalic acid kale species.

Partially SupportedSwitching to eating only animal foods improved physical performance, reduced knee pain, and led to feeling better during a long hike.

Partially SupportedConsuming raw animal fat can induce a feeling of well-being and cellular vitality.

Partially SupportedPlant-derived carbohydrate binding proteins have a higher chance of interfering with human biology than compatible molecules from animals.

Partially SupportedThe carnivore diet has lower deaths per calorie than vegan diets, unless vegetables are grown personally.

Partially SupportedPigs accumulate toxins similarly to humans because they have less effective kidneys.

Partially SupportedEating animal fat, rather than protein, is likely responsible for the feeling of well-being after consuming certain meats.

Partially SupportedPlants operate on a different biological 'operating system' than humans, leading to molecules that may not interact well with human biology.

Partially SupportedA dysregulated immune system, characterized by inflammation everywhere, indicates underlying problems that need to be addressed.

Partially SupportedIndividuals with hemochromatosis will accumulate ferritin to dangerous levels and require phlebotomy regardless of diet.

Partially SupportedPigs accumulate toxins in their bodies similarly to humans because they have inefficient kidneys and livers for detoxification.

Partially SupportedAdopting a lectin-free vegan keto, low-protein ketogenic carnivore diet will likely lead to feeling great.

Partially SupportedThallium is a toxic heavy metal that disrupts potassium in the body, inhibits mitochondrial function, and can lead to various health issues.

Partially SupportedConsuming non-grass-fed steak can lead to feeling unwell and brain fog, potentially due to glyphosate residues.

Partially SupportedEliminating plants from the diet may improve recalcitrant autoimmune conditions.

Partially SupportedFoods with fewer calories per gram than fat can be considered 'empty calories'.

Partially SupportedGut bacteria can modify the molecular structure of oral drugs, including hormones and antiviral medications.

Partially SupportedThe genetic makeup of an individual's microbiota can predict their response to medications.

Partially SupportedElevated thallium levels can impair mitochondrial function and cause kidney stones and joint pain.

Partially SupportedFor the general public, over-accumulation of iron is not a significant concern as the body is efficient at regulation.

Not SupportedWhole grains and beans may not be as beneficial as commonly believed due to toxic plant compounds like ricin.

Not SupportedKale consumption can cause gout, kidney stones, or vulvodynia in some individuals due to oxalic acid metabolism.

Not SupportedConsuming non-grass-fed meat can lead to ingesting purified synthetic estrogens derived from mycotoxins, which can cause fatty streaking in muscles.

Not SupportedDry-aged beef can be contaminated with fungus that has penetrated the muscle tissue.

Not SupportedA history of antibiotics and a raw vegan diet can lead to digestive issues and negatively impact health.

Not SupportedEating raw liver carries a risk of illness.

Not SupportedConsuming raw chicken is dangerous due to potential viruses and incompatibility with human physiology.

Not SupportedHigh protein diets are detrimental to biology, as humans primarily run on fat or carbohydrates, not protein.

Not SupportedA1 dairy is not good for humans and should be cut out of the diet for at least 32 days.

Not SupportedSmoking, barbecuing, and grilling meat are not optimal cooking methods due to health risks.

Not SupportedPythons can accumulate metals and pesticides, making them toxic.

Not SupportedThe research linking TMAO to cancer is epidemiological, not mechanistic, and therefore unreliable.

Not SupportedConsuming kale, especially raw in large quantities like in kale smoothies, can cause inflammation.

Partially SupportedA low-to-moderate protein, non-lectin, cyclical ketogenic diet is a recommended approach for health.

Not SupportedConsuming bacon cooked until it is crispy and smoked is detrimental due to high AGE formation.

Partially SupportedInhibiting mitochondrial function can lead to cytokine abnormalities and dysregulated immune responses.

Partially SupportedSystems biology is crucial for understanding complex biological interactions.

Partially SupportedApproximately two-thirds of tested drugs were modified by at least one bacterial strain, with each strain capable of modifying 11 to 95 different drugs.

Partially SupportedButter contains advanced glycation end-products (AGEs), but less than most cooked foods or bacon.

Partially SupportedIndividuals should avoid becoming insulin resistant and reverse it if they are already insulin resistant.

Partially SupportedAn ideal animal-based diet includes moderate red meat, organ meats, and healthy fats, prepared to avoid polycyclic aromatic hydrocarbons.

Partially SupportedLow fasting insulin is a stronger predictor of all-cause mortality than high fasting insulin.

Partially SupportedFood is a primary lever for modulating inflammation and autoimmunity.

Partially SupportedZearalenone is a mycotoxin that is a thousand times more estrogenic than human estrogen.

Partially SupportedPlants produce phytoalexins as defense chemicals against insects and herbivores.

Partially SupportedMeat from grass-fed and organic herds in the US rarely contains pathogens.

Partially SupportedSmall amounts of certain plants can cause severe gut cramps.

Partially SupportedConsuming smoked meat can increase inflammation the next day.

Partially SupportedMycotoxins are a significant factor in human biology.

Partially SupportedA continuous insulin monitor would be a valuable tool for tracking insulin and other metabolic markers.

Partially SupportedPostprandial insulin levels may be a more relevant marker for metabolic health than fasting insulin.

Not SupportedMany studies on medication efficacy may be inaccurate due to not accounting for individual gut microbiome variations.

Partially SupportedInteractions between bacterial strains can create toxic byproducts by modifying drugs.

Partially SupportedThe caloric density of straight oils like butter, ghee, or olive oil is very high, making them useful for increasing calorie intake without carrying excessive weight.

Partially SupportedCollagen can be consumed directly mixed with water or by eating collagenous animal tissue.

Partially SupportedSustained absence of insulin on a carnivore diet could lead to muscle loss and decreased bone density.

Partially SupportedThe speaker does not have TMAO-forming bacteria in their gut, hypothesized to be due to not eating antibiotic-fed animals.

Partially SupportedAdding a prebiotic formula that feeds butyric acid-forming bacteria increased gut bacteria species count from 48 to 196.

Partially SupportedPeople who adopt the carnivore diet are often either very curious about its effects or are very sick.

Not SupportedPrescribing statins, ACE inhibitors, and angiotensin receptor blockers did not address the root cause of patients' illnesses.

Partially SupportedFunctional medicine is a root-cause-based approach that utilizes tools like elimination diets, food allergy testing, and assessment of gut flora, inflammatory organisms, and toxic metals.

Partially SupportedThe speaker explored a raw omnivorous diet including raw steak marinated in vinegar, raw eggs, raw fish, lamb, pork, and occasionally raw chicken.

Partially SupportedHigher TMA levels in blood are associated with worse outcomes, but this association is often misinterpreted as causation.

Partially SupportedAdding lipid antioxidants like Vitamin E or BHT can prevent damage to fats during cooking.

Partially SupportedA cyclical ketogenic diet tailored to an individual's biology is recommended.

Not SupportedMarbled meat suggests a cow with metabolic syndrome, inflammation, or diabetes.

Not SupportedTMAO causation of health issues is not supported by a clear mechanism and is likely reverse causality driven by insulin resistance.

Partially SupportedHigh ferritin levels, an inflammatory compound related to iron, can be caused by high red meat intake.

Partially SupportedUsing Lugol's iodine tincture on steak can sterilize the surface, similar to how iodine is used to sterilize water for backpacking.

Partially SupportedFasting glucose levels above 90 mg/dL or A1C above 5.4% may indicate excessive protein intake.

Partially SupportedHigh protein intake, particularly from ribeye steaks, can elevate fasting glucose levels.

Partially SupportedSmoked salt, when properly prepared, can provide a smoky flavor without the harmful compounds associated with smoking meat directly.

Partially SupportedIndividuals should select vegetables based on their personal biology, including gut bacteria.

Partially SupportedConsuming raw meat can provide energy, promote fullness, and potentially lead to feeling energized or euphoric.

Partially SupportedDiets such as vegan, Bulletproof, or Paleo diets have anecdotally helped individuals improve autoimmunity and chronic inflammation.

Partially SupportedViome can predict glycemic response to foods with 90% accuracy based on gut bacteria composition.

Partially SupportedPigs prepare the soil and sheep inoculate it with necessary bacteria, contributing to soil integrity and ecosystem function.

Partially SupportedPlant-based burgers should functionally act like meat in the gut and cells to be considered a valid alternative.

Partially SupportedFixing soil health with grass-fed animals is crucial for carbon capture and sustainable food production.

Partially SupportedEating raw liver is considered good and is a social media trend.

Partially SupportedNightshades are generally bad for everyone, though some individuals tolerate them better than others.

Partially SupportedField toxins and storage toxins, such as mycotoxins, are noteworthy categories of plant toxins.

Partially SupportedCooking meat is primarily done for cleanliness and to eliminate pathogens.

Partially SupportedConsuming a handful of most plants can lead to severe illness, including hospitalization.

Partially SupportedToxic metals, such as thallium, are a concern in animal products and can bioaccumulate.

Partially SupportedThe presence of glyphosate in plant-based burgers like the Beyond Burger is a concern.

Partially SupportedTolerance to plant lectins varies individually.

Partially SupportedGlyphosate residues can be present in conventionally grown plants, even organic ones.