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Weekly · Sunday Morning

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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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The consequences of consuming alcohol — Whalespan

Content›Video›The consequences of consumin…

The consequences of consuming alcohol

Paul Saladino8m · 2022-12-03

Claims Made

14

Claims Supported

8

Support Rate

57%

Support rate

8 of 14 claims supported

8 supported6 partial / not

Claims from this content

10

✓Well SupportedChronic or excessive alcohol drinking can deplete glutathione, leaving cells vulnerable to damage from free radicals and acetaldehyde.✓Well SupportedAlcohol consumption, from light to heavy, reduces brain cortical thickness in a dose-dependent manner.✓Well SupportedFrying with vegetable oils can produce acrolein, a health hazard and a cause of lung cancer.✕Not SupportedIf fasting insulin is above 5, alcohol consumption should be avoided.◐Partially Supported

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AV

A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

NP

N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

Alcohol is an oxidative stressor comparable to cigarettes.

◐Partially SupportedAlcohol is poisonous and bad for the brain, even if fasting insulin is below 5.

◐Partially SupportedFasting insulin levels are a proxy for linoleic acid levels and metabolic health.

✕Not SupportedIndividuals with high cellular linoleic acid content should avoid alcohol, diesel fumes, heavy metals, and cigarettes.

✕Not SupportedAlcohol is an oxidative stressor comparable to cigarettes and can contribute to oxidizing LDL, atherosclerosis, macular degeneration, endothelial dysfunction, and erectile dysfunction.

◐Partially SupportedAn individual's susceptibility to oxidative stress is determined by their cellular linoleic acid content.