The real reasons behind most modern symptoms

PS

Paul Saladino1h 7m · 2024-03-19

Claims Made

119

Claims Supported

87

Support Rate

73%

Support rate

87 of 119 claims supported

87 supported32 partial / not

Claims from this content

94

Well SupportedRaw milk consumption is associated with lower rates of asthma, eczema, and allergies in children.Well SupportedRiboflavin is crucial for methylation reactions, particularly for individuals with MTHFR polymorphisms, and can help a 'broken' MTHFR enzyme function optimally.Well SupportedNatural folate precursors and riboflavin, abundant in organ meats like heart and liver, are crucial for supporting MTHFR function.Well SupportedAdequate riboflavin intake (e.g., 1.6mg, above RDA) may allow the MTHFR enzyme to function effectively, normalizing homocysteine levels even with the 677 C to T variant.Well Supported

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A. Volkovreader

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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

The eatlineage meat stick contains no celery powder, lactic acid, stabilizers, artificial sweeteners, fake chemical ingredients, hormones, or antibiotics.

Partially SupportedFolic acid is a synthetic form of folate that does not occur in nature and can lead to unabolized folic acid in the body.

Well SupportedChecking homocysteine levels and monitoring overall well-being are indicators of methylation process efficiency.

Partially SupportedThe speaker's homocysteine levels are typically 10-11 unless they consume liver or a small amount of L-5-methylfolate or folinic acid.

Partially SupportedThe speaker identifies as a 'poor methylator' due to MTHFR gene polymorphisms.

Partially SupportedProcessed foods lacking micronutrients and complete information contribute to inflammation and incomplete bodily programming.

Well SupportedMethylated B vitamin supplements may be beneficial for individuals with MTHFR, COMT, or other methylation cycle polymorphisms.

Partially SupportedSome dense carbon filters, like those from Berkey, may require a post-filter to remove fluoride and can introduce aluminum oxide contamination.

Partially SupportedThere is a correlation between folic acid fortification and increased rates of ADHD and impulse control disorders.

Partially SupportedMany people are deficient in basic nutritional components like essential minerals, fatty acids, and amino acids.

Well SupportedBreathwork utilizing auxiliary respiratory muscles can be a free alternative to hyperbaric oxygen systems.

Partially SupportedModifiable risk factors in diet, lifestyle, routines, medications, supplementation, and food supply are the primary reasons people do not live longer, healthier, happier, or more fulfilling lives.

Partially SupportedA National Toxicology Program survey found an inverse relationship between IQ and fluoride concentration in prepubescent children.

Partially SupportedFluoride and other neurotoxins can have significant detrimental effects during fetal and adolescent neurodevelopment.

Not SupportedDrinking fluoride may not provide dental anti-decay benefits and introduces a neurotoxin into the body.

Partially SupportedProviding raw materials like folate and riboflavin can address issues related to MTHFR gene function.

Partially SupportedAnemia can be present even when red blood cell count and hemoglobin levels are within the lower range of normal, indicating poor oxygen transport.

Partially SupportedFor individuals with the MTHFR gene variant who have issues processing folic acid, switching to methylfolate and methylcobalamin can resolve anemia.

Partially SupportedCyanocobalamin, a form of B12, is hydrogen cyanide-based and cyanide is toxic to mitochondria.

Partially SupportedThe body converts cyanocobalamin into hydroxycobalamin, suggesting hydroxycobalamin or methylated cobalamin forms are preferable for absorption and utilization.

Well SupportedIt is difficult for most individuals to obtain all necessary nutrients solely through diet, requiring careful planning and specific food choices.

Not SupportedFortified cereals may contain synthetic folic acid and cyanocobalamin, which are less desirable forms of folate and B12.

Well SupportedNutritional density is strongly linked to the brain's satiation response, and under-nutrition can lead to overeating.

Partially SupportedCyanocobalamin is a form of vitamin B12 that contains cobalt metal bound to hydrogen cyanide.

Partially SupportedFluoride used in water fluoridation is hydrofluosilicic acid, a hazardous waste byproduct.

Partially SupportedCOMT is an enzyme that transfers a methyl group from catecholamines.

Not SupportedFluoride should be permanently removed from our lives due to its cumulative toxicity.

Partially SupportedIndividuals with slow COMT enzyme activity may have higher levels of catecholamines, leading to increased worry.

Partially SupportedSupplementing to regulate COMT enzyme function can significantly improve life by influencing estrogen metabolism down the E2 pathway.

Partially SupportedStudies in rats show that removing fluoride from drinking water leads to decalcification of the pineal gland.

Partially SupportedMTHFR, MTRR, and COMT are key genes in the methylation cascade.

Partially SupportedThe MTHFR gene mutation can predispose individuals to anxiety.

Partially SupportedGetting a gene test for MTHFR is recommended for most people.

Partially SupportedOver 44% of the population has an MTHFR gene mutation.

Partially SupportedToothpaste containing fluoride has warning labels regarding ingestion by children.

Not SupportedEating a banana increases glycemic index more than blending a banana.

Partially SupportedThe concentration of fluoride in recommended daily water intake is four times the level in a pea-sized amount of toothpaste.

Partially SupportedAmino acid deficiencies can lead to neurotransmitter deficiencies, impacting mood and behavior.

Partially SupportedActionable genetic information can be correlated with nutrient deficiencies and disease expression.

Partially SupportedConsuming Celtic salt or Baja gold salt in drinking water and ensuring adequate amino acid intake are basic foundational health practices.

Partially SupportedConsistent overthinking, worrying, or considering worst-case scenarios, especially at night, may indicate a COMT gene mutation.

Partially SupportedContinuous eating from morning to night prevents cellular autophagy and immune system cleanup.

Partially SupportedFoundational health practices such as diet, lifestyle, spiritual well-being, whole foods, clean water, sun exposure, grounding, breathwork, and cold showers act as hormetic stressors that can change health trajectories.

Partially SupportedDeficiencies in methylation cycle enzymes, due to genetic factors or nutrient deficits, can significantly impact the entire methylation cycle.

Partially SupportedGenetic variations like COMT are actionable genes whose function can be supplemented to improve health outcomes.

Partially SupportedPoor oxygen transport and delivery, as seen in anemia, accelerates the onset and severity of nearly every studied disease.

Partially SupportedPet kefir from Raw Farm is the same quality as human kefir and safe for human consumption.

Not SupportedFluoride may prevent tooth decay by forming a nanoparticulate layer over the tooth, but this can be achieved by brushing with hydroxyapatite.

Partially SupportedThe body can convert cyanocobalamin into hydroxycobalamin, suggesting hydroxycobalamin or methylated cobalamin are preferable forms of B12.

Not SupportedTaking excessive methylfolate can lead to over-methylation, requiring caution and monitoring of homocysteine levels.

Not SupportedWestern medicine is associated with the highest rates of obesity and diabetes globally.

Partially SupportedAdopting an ancestral diet and lifestyle is a simpler and more effective approach to health than complex biohacking.

Partially SupportedA health company is gathering big data from approximately 20,000 new patients per month, including blood work, gene tests, supplement usage, and measurable outcomes like C-reactive protein, alkaline phosphatase, GFR, and homocysteine, alongside subjective reports of improved sleep, libido, clarity, and energy.

Partially SupportedCobalt is the metal component of B12 (cobalamin), and B12 is a necessary trace metal.

Partially SupportedSunlight exposure and earthing can provide benefits similar to expensive technologies.

Partially SupportedFunnel cake, deep-fried in oils and served with added sugar, is a highly processed food contributing to poor health.

Partially SupportedChanging diet quality to align with ancestral eating patterns can improve many health issues including depression, anxiety, obesity, and insomnia.

Partially SupportedA 64-ounce Big Gulp contains approximately 38-39 teaspoons of sugar.

Partially SupportedGiving children a week off from folic acid is a reasonable consideration.

Partially SupportedIndividuals with MTHFR mutations may experience severe symptoms if they consume folic acid and processed grains.

Partially SupportedMethylfolate converts homocysteine into methionine, which can downregulate catacholamines.

Partially SupportedThe MTHFR gene mutation can impact physiology and potentially lead to methylfolate deficiencies.

Partially SupportedSome individuals who believe they have a gluten sensitivity may actually be sensitive to folic acid, as it is commonly added to similar processed foods.

Partially SupportedMothers with the highest folate levels had newborns with telomeres that were 10% longer.

Partially SupportedMethylfolate helps convert homocysteine into methionine.

Partially SupportedDopamine synthesis is iron-dependent, while serotonin and melatonin synthesis depend on B6 and methylated B vitamins.

Partially SupportedPaul Saladino has homozygous MTHFR gene mutations (677 C>T and 1298 A>C) which may predispose him to anxiety.

Partially SupportedAmino acids are essential for building immune cells, red blood cells, hemoglobin, and neurotransmitters like serotonin and dopamine.

Partially SupportedNutrient deficiencies can cause pathology in humans, similar to how a lack of nitrogen in soil can cause a palm tree leaf to rot and heal upon correction.

Partially SupportedAvoiding processed foods like pasta with folic acid, cyanocobalamin, industrial byproducts, and fluoridated water is recommended for better health.

Partially SupportedDeficiencies in CoQ10, folate, and vitamin D3 have been shown to impact bone mineralization and cardiovascular health.

Partially SupportedAnecdotes from people improving their health through dietary changes can be considered valid evidence.

Partially SupportedWater filtration systems can remove environmental and toxic loads from the body.

Partially SupportedDoctors rarely inform patients that dietary changes aligned with ancestral patterns can resolve common health issues.

Partially SupportedChlorine can be absorbed transdermally through the skin in as little as 60-90 seconds of contact with tap water.

Partially SupportedMethionine can enter the brain and downregulate catecholamines, which are fight-or-flight neurotransmitters.

Partially SupportedMany modern health issues stem from nutrient deficiencies rather than inherent illness.

Partially SupportedGut issues, mild anxiety, and interrupted sleep can stem from nutrient deficiencies.

Partially SupportedMethylation is a complex process relevant to personalized nutrition.

Partially SupportedMTHFR stands for Methylene Tetrahydrofolate Reductase.

Not SupportedTraditional treatment for anemia with iron, B12, and folic acid can lead to subsequent issues like anxiety, heart palpitations, and severe sleep problems.

Partially SupportedHumans are generally poor at making long-term horizon judgments, often prioritizing immediate gratification over future benefits.

Partially SupportedWater filters can remove chlorine, fluoride, pharmaceuticals, glyphosate, and microplastics.

Partially SupportedFour-stage reverse osmosis filters are effective at removing fluoride from water.

Partially SupportedWater filters are a worthwhile long-term investment.

Partially SupportedChlorine can be absorbed transdermally from water within 60 to 90 seconds.

Partially SupportedSimple lifestyle practices such as sun exposure, grounding, eating whole animal foods including organs, and consuming meat and whole plant foods in an ancestrally consistent way can significantly improve health.

Partially SupportedNutritionally, raw milk is not different from pasteurized milk.

Partially SupportedPaul Saladino takes 1,000 micrograms of methylfolate, titrating the dose.

Partially SupportedCumulative dosage, not just single doses, often determines toxicity for substances like mercury and fluoride.