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Rapamycin extends mouse lifespan 9–14%
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Risks and benefits of DHEA supplementation | Peter Attia & Derek MPMD — Whalespan

Content›Video›Risks and benefits of DHEA s…

Risks and benefits of DHEA supplementation | Peter Attia & Derek MPMD

Peter Attia7m · 2024-03-08

Claims Made

13

Claims Supported

4

Support Rate

31%

Support rate

4 of 13 claims supported

4 supported9 partial / not

Claims from this content

8

✓Well SupportedIn women, DHEA supplementation can increase total testosterone levels by approximately 4-fold, restoring levels to baseline while on suppressive oral contraceptives.✕Not SupportedDHEA supplementation carries a worse risk-to-reward ratio for women due to the common side effect of acne.✕Not SupportedOral DHEA has no discernible utility or effect on testosterone levels in males and may cause a spike in estrogen.✓Well SupportedDirect measurement of DHEA in blood is not as indicative of the total body pool because the majority of DHEA is sulfated.Partially Supported

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AV

A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

◐

DHEA is available over-the-counter in the United States, unlike in Canada where it is a Schedule I drug.

◐Partially SupportedWomen may be more sensitive to DHEA supplementation than men due to adrenal androgen synthesis.

◐Partially SupportedDHEA sulfate is the standard proxy for measuring DHEA levels in blood work.

◐Partially SupportedDHEA is a banned substance by WADA and USADA.