Food Vs Medicine And Are Humans Really Carnivores

PS

Paul Saladino1h 26m · 2019-10-31

Claims Made

141

Claims Supported

104

Support Rate

74%

Support rate

104 of 141 claims supported

104 supported37 partial / not

Claims from this content

110

Well SupportedAll vitamins and minerals found in plants can be obtained from animal sources in more bioavailable forms.Well SupportedHumans have historically relied on animal foods as the primary source of protein and nutrients.Well SupportedMetabolic dysfunction, specifically insulin resistance, is the primary event leading to atherosclerosis, not LDL directly injuring the endothelium.Well SupportedIt is possible to obtain 60 mg of vitamin C daily by eating animal foods nose-to-tail, with liver being richer in vitamin C than muscle meat.Well Supported

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A. Volkovreader

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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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N. Park

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Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

When Framingham data is not stratified by metrics associated with insulin resistance, LDL cholesterol shows a linear correlation with cardiovascular disease incidence.

Well SupportedRandomized controlled trials showing that red meat is not inflammatory should be considered as part of the overall body of evidence.

Well SupportedOrgan meats are crucial for filling nutritional gaps not met by muscle meat or plants and are historically treasured for their nutrient density.

Well SupportedMany essential nutrients for humans are only found in red meat.

Well SupportedAtherosclerosis does not develop in veins, suggesting that endothelial damage is necessary for its initiation.

Well SupportedOrgan meats like liver, heart, spleen, kidney, and pancreas were considered part of 'meat' by ancestors and should be included in the diet for improved quality of life.

Well SupportedHumans likely consumed meat with saturated fat throughout evolution, and meat consumption may have driven brain growth.

Well SupportedA vitamin C dose as low as 10 milligrams per day was sufficient to correct scurvy in studies from the 1930s and 40s, with no observed clinical benefit from higher doses.

Well SupportedStudies show resolution of idiopathic constipation when fiber is removed, contradicting the necessity of fiber for bowel movements.

Well SupportedOrgan meats contain crucial trace minerals not found in muscle, such as retinol, folate, choline, and riboflavin.

Not SupportedFocusing solely on LDL cholesterol as the sole indicator of cardiovascular risk is a poor predictor.

Not SupportedWestern medicine often fails to appreciate the profound impact of food on inflammatory, autoimmune, dermatological, and psychiatric diseases.

Well SupportedPlants have evolved defense chemicals over millions of years because they are immobile and cannot escape predators, unlike animals which can run, kick, or bite.

Well SupportedA nose-to-tail carnivore diet provides the highest amount of bioavailable micronutrients with the least amount of toxins.

Not SupportedNative LDL cholesterol alone is not sufficient to cause atherosclerosis.

Well SupportedInsulin sensitivity is the most significant factor in reducing cardiovascular risk.

Well SupportedDr. Paul Saladino has used a nose-to-tail carnivore diet to reverse untreatable autoimmunity, chronic inflammation, and mental health issues in hundreds of patients.

Well SupportedIn Asian cultures, populations that consume the most meat exhibit the longest lifespans and lowest rates of cardiovascular disease and cancer.

Well SupportedIndividuals with inflammatory bowel disease may experience negative effects from increased fiber intake.

Well SupportedMeat is generally a poor source of vitamin C, with most beef items containing only tiny amounts, though some organ meats contain slightly more.

Not SupportedEpidemiological studies cannot definitively answer questions about the health effects of specific foods like meat.

Not SupportedFiber does not improve the quality of stool, reduce pain with passing stool, decrease the need for laxatives, or lessen bleeding associated with constipation.

Not SupportedIncreasing fiber intake is not necessarily required for a healthy microbiome, and decreasing fiber does not automatically lead to an unhealthy microbiome.

Not SupportedIncreased fiber intake does not increase alpha diversity in the gut microbiome.

Well SupportedDesired biochemical pathways can be activated through environmental hormetics such as heat, cold therapy, exercise, and ketosis, without relying on plant molecules.

Well SupportedDamage to the arterial endothelium's glycocalyx allows LDL to enter the arterial wall and initiate atherosclerosis.

Well SupportedEnvironmental hormetic stressors like sun exposure, cold water, and saunas strengthen the body's antioxidant system.

Partially SupportedAdding a small amount of vitamin C supplement is not harmful if individuals are concerned about their intake, although clinical evidence for its necessity is lacking.

Partially SupportedThe transition from a hunter-gatherer diet to a pastoralist diet with more grains led to a decline in human health.

Well SupportedHigh levels of beta-glucuronidase can indicate dysbiosis and lead to the recirculation of estrogen.

Partially SupportedPlants produce defense chemicals like thorns, hard shells, and toxic compounds as a co-evolutionary response to herbivory.

Not SupportedTriglyceride/HDL ratio, fasting insulin, and c-peptide are crucial for understanding cardiovascular disease risk.

Partially SupportedIn a protein-rich diet lacking sufficient fiber, protein fermentation can produce isobutyrate, which can fulfill many of butyrate's signaling functions in the gut.

Partially SupportedEating liver raw from hunted animals was a sacred practice to prevent nutritional deficiencies.

Partially SupportedConsuming the whole animal, including organ meats and bones, is a strategy for thriving on a carnivore diet.

Partially SupportedFood is the most significant factor influencing health and disease, outweighing drugs.

Partially SupportedHormesis from sulforaphane may activate endogenous systems like Nrf2 and increase glutathione.

Partially SupportedStudies that lower LDL cholesterol have consistently shown better health outcomes compared to those that do not.

Partially SupportedThe removal of fiber from the diet is not harmful and can be helpful in certain clinical conditions.

Partially SupportedPlants are considered survival or fallback foods, providing just enough calories to sustain individuals until they can hunt again.

Not SupportedPlant-based diets can be nutrient-deficient long-term and may contain toxins that trigger immune or inflammatory responses.

Partially SupportedRemoving fruits and vegetables from the diet can lead to improved oxidative stress markers.

Partially SupportedThere is significant genetic variability in how well individuals tolerate plant foods.

Partially SupportedModern exercise paradigms are shifting towards functional training that translates to real-world activities.

Partially SupportedEating fresh meat prevents scurvy because preservation processes can destroy vitamin C.

Partially SupportedAnimal protein, specifically meat, is more bioavailable than plant-based proteins and contains unique nutrients associated with improved athletic performance.

Partially SupportedHumans have approximately 4 million years of hominid and pre-hominid evolution, during which meat consumption increased and may have fueled brain size growth.

Partially SupportedThe narrative that red meat is harmful and vegetables are beneficial has been a recent development, potentially a reversal of historical perspectives.

Not SupportedPlant defense chemicals do not have a clear hormetic effect in humans and their negative effects outweigh potential hormesis.

Partially SupportedThe speaker believes that the human body is designed to move and that exercise is necessary.

Partially SupportedThe goal of an animal-based diet is to maximize variety while keeping nutrient levels high and toxins low for human thriving.

Partially SupportedHuman biology and biochemistry are fundamentally adapted for animal foods as the primary fuel source.

Partially SupportedFood molecules can act as signals to the body similar to drugs but are consumed in much larger quantities.

Partially SupportedLDL has beneficial immunologic roles, protecting against bacterial infection, particularly as individuals age.

Partially SupportedReducing plant-based fiber intake leads to improvements in gastrointestinal symptomatology and overall health.

Partially SupportedThere is no evidence that red meat is inflammatory.

Partially SupportedWestern medicine should prioritize food as a primary tool for improving disease outcomes, maintaining health, and achieving optimal health.

Well SupportedExtending lifespan and healthspan are current areas of focus, alongside enjoying life and cultivating good health, including mental health.

Not SupportedStatin side effects can include mitochondrial targeting leading to muscle wasting, and some statins can inhibit cholesterol synthesis in the brain.

Partially SupportedChaga possesses powerful antioxidant, anti-cancer, and immune system regulating properties.

Partially SupportedConsuming animal connective tissue is beneficial for gut health as it can be fermented to short-chain fatty acids.

Partially SupportedPlant fiber is not required for a healthy gut microbiome; animal fiber or collagen can be used as alternatives.

Partially SupportedCarnivore diets can produce short-chain fatty acids that colonic epithelial cells can utilize.

Partially SupportedAlpha diversity of the gut microbiome does not increase when fiber is added to high-fat ketogenic diets.

Partially SupportedConsuming more fiber does not necessarily lead to a reduction in cancer rates.

Not SupportedVitamin C supplementation does not improve health outcomes in people with sufficient levels.

Partially SupportedConsuming plants can cause severe health issues like rheumatoid arthritis, eczema, or ulcerative colitis in some individuals.

Not SupportedXeno-hormetic compounds like isothiocyanates can cause collateral damage, including inhibiting thyroid hormone production and causing lipid peroxidation.

Partially SupportedVegetarians and plant-based eaters often have lower levels of essential nutrients like carnitine, creatine, choline, vitamin K2, and B12, leading to suboptimal function.

Partially SupportedNatural immunomodulators support a healthy immune system by both elevating and calming it as needed.

Not SupportedPolyphenols and isothiocyanates consumed for 4-6 weeks do not show measurable benefits in glutathione levels, oxidative stress, immune response, or inflammation markers compared to control groups.

Partially SupportedCardiologists should consider triglyceride to HDL ratio and inflammatory markers alongside LDL cholesterol for cardiovascular risk assessment.

Not SupportedThe necessity of high vitamin C intake for human health may be overstated, as supplementation does not consistently show benefits.

Partially SupportedGenetic polymorphisms can affect an individual's ability to convert beta-carotene to vitamin A from plants.

Partially SupportedVitamin C functions in the aqueous compartment of cells to help regenerate glutathione, a major player in cellular redox reactions.

Partially SupportedMeasures of malabsorption like stool elastase, calprotectin, and lactulose mannitol tests are more clinically relevant indicators of gut health than microbiome composition alone.

Partially SupportedConstipation may be caused by fiber, potentially by feeding methane-producing organisms or triggering other gut problems.

Partially SupportedEvery human is biologically adapted to eat animal foods, with varying degrees of tolerance for plant foods.

Partially SupportedMushroom coffee mix containing cordyceps and chaga provides a feeling of well-being without a caffeine spike and crash.

Not SupportedEpidemiological studies relying on self-reported dietary intake are confounded by unmeasured variables.

Not SupportedThere is no need for increased glutathione levels if one is living a 'radical life' with sufficient hormetic stress.

Partially SupportedThe most important question regarding diet is which diet promotes the best health for an individual, with potential for variation between individuals.

Partially SupportedDiets with and without fruits and vegetables for 4-6 weeks show no significant differences in glutathione, oxidative stress, inflammation, or immune activation.

Partially SupportedIn a healthy physiological state, the body should not require additional interventions to eliminate excess estrogens.

Partially SupportedHigher blood levels of vitamin C are associated with better health, but this correlation may be confounded by other healthy behaviors.

Partially SupportedThe recommended dietary allowance for vitamin C is 60 mg for women and 80-90 mg for men.

Partially SupportedXeno-aromatic compounds in plants activate antioxidant response elements in the body because they are inherently toxic.

Partially SupportedPlants may contribute to dysbiosis, leading to the recirculation of estrogen.

Partially SupportedType 2 diabetes can be reversed.

Partially SupportedChaga mushroom extract has been clinically shown to increase Natural Killer (NK) cell activity by over 300%.

Partially SupportedA diet high in animal foods, excluding insulin-resistant processed carbohydrates, can lead to weight loss, improved diabetes, increased insulin sensitivity, and better lipid panel markers.

Partially SupportedHumans retained the ability to digest plants, providing an evolutionary survival benefit during periods of unsuccessful hunting.

Not SupportedEpidemiology studies often fail to account for confounding variables like marital status, financial well-being, and exercise habits.

Partially SupportedThe cause of atherosclerosis was unknown 30 years ago, but is now largely understood.

Not SupportedNutrient density is a potentially misleading metric; bioavailability and nutrient richness are better measures of a food's nutritional value.

Partially SupportedThe Inuit diet, averaging about 40 mg of vitamin C daily from animal foods, does not typically result in scurvy.

Partially SupportedCorrelation does not imply causation, as demonstrated by spurious correlations between unrelated variables like Nicolas Cage movies and violent deaths.

Not SupportedA healthy microbiome is defined by its state in a healthy individual, rather than by the presence of specific bacteria.

Partially SupportedPrimate brain size remained consistent for 30 million years on plant-based diets.

Partially SupportedRemoving fiber improves gut health measures, including inflammation and gut permeability.

Not SupportedPlant defense molecules like phytoalexins and isothiocyanates may have questionable long-term benefits to humans.

Partially SupportedPlanks are a common exercise today, having gained popularity over the last 20 years.

Partially SupportedOnnit popularized functional training tools like steel maces, steel clubs, and battle ropes.

Partially SupportedMarkers of oxidative stress and glutathione levels appear normal in individuals consuming an animal-based diet.

Partially SupportedAvoiding heart attack, stroke, and diabetes can be achieved through practices like back bends and surfing.

Partially SupportedFeeling good in life is characterized by positive mood, good body image, libido, energy, and quality sleep.