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Weekly · Sunday Morning

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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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Can Humans Become Physically Immortal? | Brian Kennedy, Ph.D. — Whalespan

Content›Video›Can Humans Become Physically…

Can Humans Become Physically Immortal? | Brian Kennedy, Ph.D.

Peter Attia11m · 2025-07-22

Claims Made

16

Claims Supported

9

Support Rate

56%

Support rate

9 of 16 claims supported

9 supported7 partial / not

Claims from this content

12

✓Well SupportedIncreasing research funding for the biology of aging would be beneficial for late-life health.✓Well SupportedCardiovascular disease is the most preventable of the major disease categories (atherosclerosis, cancer, neurodegenerative disease) due to better understanding of its pathology and more effective prevention tools.◐Partially SupportedThe drivers of aging may be similar between mice and humans, even if the downstream events differ.◐Partially SupportedCancer may be less modifiable by longevity interventions compared to dementia, metabolic, and cardiovascular diseases.Partially Supported

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Attia walks back the clinic protocol: too aggressive for healthy adults

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AV

A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

◐

Inflammation and the immune system may be primary drivers of Alzheimer's and other dementias.

✕Not SupportedAn intense focus on one or two mechanisms in Alzheimer's research may have led to neglecting other disease drivers.

◐Partially SupportedMetabolic diseases are modifiable, similar to cardiovascular disease.

◐Partially SupportedCancer may be less modifiable by longevity interventions compared to cardiovascular and metabolic diseases.

◐Partially SupportedPreserving healthspan in the last decade of life by addressing frailty, cognitive decline, and pain is a practical goal.

◐Partially SupportedStudying neurogenic changes in aging mice may provide more insight into Alzheimer's than artificial models because aging drivers might be similar to Alzheimer's drivers.

◐Partially SupportedCardiovascular diseases are the most preventable major diseases due to a strong understanding of their causes and interventions, and they are responsive to lifestyle modification.

◐Partially SupportedEven centenarians and supercentenarians exhibit significant physical frailty and sarcopenia, comparable to individuals much younger.