The importance of VO2 max, muscle mass, and muscular strength for lifespan

Well SupportedHigh VO2 max, muscle mass, and strength are superior predictors of lifespan compared to cholesterol, blood pressure, blood glucose, and smoking.

Partially SupportedHigh grip strength implies a history of lifting, carrying, and aggressively using hands, reflecting accumulated work.

Partially SupportedStrong grip strength and high VO2 max are superior predictors of lifespan compared to factors like smoking, drinking, or family history of cancer.

Not SupportedSupplements like resveratrol, NMN, metformin, and rapamycin are less important than cardiorespiratory fitness and muscle strength for healthspan.

Partially Supported