Eating meat reverses aging

PS

Paul Saladino55m · 2023-08-01

Claims Made

163

Claims Supported

127

Support Rate

78%

Support rate

127 of 163 claims supported

127 supported36 partial / not

Claims from this content

126

Well SupportedFor general overall health, a daily creatine dose of approximately 0.1 g per kilogram of body weight is recommended.Well SupportedCreatine supplementation, at approximately 5 grams per day for a 180-pound individual, enhances muscle performance, power output (12-20%), hydration, and reduces fatigue.Well SupportedVitamin K2 is synthesized by bacteria during fermentation and is not found in plant foods.Well SupportedTaurine is a unique nutrient found in animal foods, not plant foods, and has been studied for longevity benefits across multiple species.Well Supported

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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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Taurine levels decline with aging and taurine supplementation extended lifespan in mice.

Well SupportedPlant-based protein is at least twice less bioavailable than animal protein.

Partially SupportedIncreased creatinine levels due to creatine or high meat intake are not harmful and may warrant cystatin C testing for kidney function assessment.

Well SupportedHeart & Soil supplements are freeze-dried and sourced from grass-fed, regeneratively raised animals in New Zealand.

Well SupportedMeat, especially red meat, is a longevity food containing unique nutrients associated with longevity and decreased disease states.

Not SupportedFish can contain heavy metals, PFAS, endocrine disruptors, and microplastics, making them a polluted food source.

Not SupportedFolic acid should be avoided in supplements and food due to poor conversion and potential issues with unmetabolized folic acid.

Well SupportedIndividuals supplementing with creatine or consuming a high-meat diet should also measure cystatin C in addition to creatinine to accurately assess kidney function.

Well SupportedOrgan meats, dark meat chicken, slow-twitch muscles, and beef cheeks are good food sources of taurine.

Well SupportedAnimal foods, particularly meat and organs, are rich sources of creatine, choline, carnitine, carnosine, taurine, K2, and B12, nutrients not found in plant foods.

Well SupportedElevated creatinine levels in blood tests for individuals supplementing with creatine may not indicate kidney damage.

Well SupportedA recommended protein intake for an animal-based diet is approximately 1 gram of protein per pound of lean body weight or total body weight.

Well SupportedTaurine supplementation has shown improvements in blood pressure, muscle cramps, stroke-like episodes, endurance, and cardiovascular function in patients with CHF.

Well SupportedVitamin K2 is found in animal foods and is essential for calcium movement, potentially reducing heart disease and aortic valve calcification.

Well SupportedNot obtaining taurine, carnosine, alanine, creatine, and 4-hydroxyproline in the diet leads to deficiency and suboptimal levels not conducive to longevity.

Well SupportedOlder adults may require higher creatine intake due to age-related decreases in muscle creatine levels.

Well SupportedMeat and organs contain unique nutrients like taurine and creatine, and deficiencies in these are not well-quantified.

Well SupportedEating organs provides nutrients not found in vegetables and enhances overall health.

Well SupportedVegetarians and omnivores have similar all-cause mortality rates.

Well SupportedDry cooking methods like grilling and rare to medium-rare meat preserve more taurine than boiling, stewing, or overcooking.

Well SupportedBeef cheek meat has approximately five times higher taurine content than other parts of the animal, and taurine is associated with beneficial cardiovascular outcomes.

Well SupportedCreatine is a well-researched ergogenic substance exclusively found in appreciable quantities in animal foods.

Well SupportedVitamin B12 is not found in any plant foods globally.

Well SupportedAnecdotal reports suggest that women struggling with breastfeeding have experienced improvements in milk letdown and production after drinking raw cow's milk.

Well SupportedMeat, particularly grass-fed and grass-finished, is a health food for humans and is full of nutrients that help humans thrive.

Well Supported4-hydroxyproline, found in collagen and animal foods, has numerous studies supporting its benefits for skin health and potentially longevity.

Partially SupportedThe human body produces approximately 1.7 grams of creatine per day.

Well SupportedThe human body does not produce sufficient amounts of taurine, carnosine, alanine, creatine, and 4-hydroxyproline, making dietary intake beneficial.

Well SupportedRed meat is a health food containing nutrients like taurine, which are difficult to find elsewhere and linked to improved human health.

Well SupportedResearch on taurine and carnosine shows benefits across animal models, and similar benefits are suspected for human longevity.

Well SupportedRed meat can be incorporated into a healthy diet.

Well SupportedThe animal-based 30 is a 30-day challenge to help individuals start an animal-based diet.

Well SupportedRed meat contains unique nutrients such as taurine, alanine, carnitine, carnosine, B12, 4-hydroxyproline, and creatine, which are not found in plant foods.

Partially SupportedIndividuals who eat more red meat in epidemiological studies are often less healthy, more obese, exercise less, have more disease, smoke more, and drink more alcohol.

Partially SupportedNutrients in red meat like creatine, carnitine, choline, and taurine may improve longevity and DNA protection.

Partially SupportedA diet centered around unprocessed red meat is unlikely to be detrimental to human health and longevity.

Partially SupportedCreatine is crucial for muscle strength, lean body mass, recovery, resilience, avoiding sarcopenia, and neurological/muscular/immunologic/cognitive function, all of which are associated with longevity.

Partially SupportedTaurine, carnosine, anserine, creatine, and 4-hydroxyproline are absent or negligible in plant-source foods.

Partially SupportedTaurine improves vascular function in individuals with Type 2 Diabetes.

Partially SupportedPeople who consume more red meat in epidemiological studies may also engage in more unhealthy behaviors, confounding the results.

Not SupportedThe idea that red meat is bad for humans is contradicted by its numerous beneficial nutrients that contribute to longevity.

Partially SupportedModerate meat consumption is associated with benefits in Asian prospective cohort studies.

Partially SupportedA dietary intervention of folic acid, B12, and flavonols modified DNA methylation age.

Partially SupportedMany reputable creatine brands provide certificates of analysis indicating clean sourcing.

Partially SupportedMany ex-vegans report health improvements using beef organ supplements to reintroduce animal foods.

Partially SupportedNutrient-rich food, defined as whole animal food without plant toxins, is the optimal human diet.

Partially SupportedRed meat is a health food for humans.

Partially SupportedWell-raised meat from grass-fed animals provides unique nutrients not found in plants.

Partially SupportedAn increase in LDL cholesterol from consuming more saturated fat from animal foods and less seed oils does not necessarily indicate an increase in cardiovascular risk.

Partially SupportedDecreased red meat consumption in humans correlates with becoming less healthy.

Not SupportedThe scientific argument for vegan diets being superior for longevity collapses concerning nutrient intake.

Partially SupportedOne pound of meat contains 1.5-2 grams of creatine, and one liter of milk contains about 1 gram.

Partially SupportedTaurine is essential for conjugating bile acids into bile salts, facilitating intestinal lipid absorption.

Not SupportedThe speaker avoids fish due to concerns about microplastics, PFAS, and heavy metals.

Partially SupportedA recommended daily intake for meat is approximately one gram of predominantly grass-fed red meat per pound of gold body weight.

Partially SupportedNutrients like vitamin K2, choline, carnitine, carnosine, taurine, B12, riboflavin, and folate are found in meat and organs but not on regular nutrition labels.

Partially SupportedConsuming beef organs can provide refreshment and energy when feeling sluggish.

Well SupportedCollagen hydrolysate at 10g per day for 24 weeks improved bone mineral density and mitigated osteoporosis in postmenopausal women.

Partially SupportedThree grams of creatine per day for weeks or months improves antioxidant capacity, exercise performance and recovery, and neurological/muscular function.

Partially SupportedA 100g serving of beef heart contains 22mg of taurine.

Partially SupportedChanges in diet, such as increasing saturated fat and reducing seed oils, can lead to elevated LDL cholesterol in some individuals.

Partially SupportedCarnosine at 2g/day for three months improved neurological function in patients with schizophrenia.

Partially SupportedCreatine is found in red meat, chicken, fish, and pork, but not in plant foods.

Partially SupportedCollagen hydrolysate at 2.5g or 5g per day for 8 weeks improved the structure of the collagen network and facial skin conditions in adult women.

Well SupportedDietary supplemental creatine (20g/day for 5 days or 2g/day for 30 days) increases skeletal muscle creatine phosphocreatine.

Partially SupportedConsuming over half a kilogram of meat daily provides hundreds of milligrams of taurine and carnosine.

Partially SupportedEating whole foods, including red meat and organs, provides unique and beneficial nutrients.

Partially SupportedThree grams of taurine per day for 60 days improved blood pressure in patients with mild or borderline hypertension.

Not SupportedGaining muscle on a vegan diet may require significant amounts of synthetic processed vegan protein powders, raising questions about their long-term health implications.

Partially SupportedVitamin B12, found exclusively in animal foods, is crucial for preventing dementia, neurocognitive decline, and neurological dysfunction with age.

Partially SupportedDoses of carnosine studied in human clinical trials are obtainable from eating animal foods.

Partially SupportedCarnosine at 0.8g/day for eight weeks improved behavior, social skills, and communication skills in patients with autism.

Partially SupportedCarnosine supplementation at 16mg/day for 8 weeks enhanced gastric healing in patients with gastric ulcers.

Partially SupportedAnimal foods, particularly grass-fed grass-finished red meat, are generally better for humans than fish and do not contain defense chemicals like many vegetables.

Partially SupportedSupplementation with folic acid and B12 can increase global DNA methylation levels in unmethylated regions.

Partially SupportedWomen who took supplements of folic acid and B12 showed slower biological aging, and could achieve similar benefits by eating meat, organs, and liver.

Partially SupportedThe argument that a plant-based diet is better for longevity is a common discussion point.

Partially SupportedNutrients that contribute to multiple aspects of human health, such as longevity, lean body mass, and cognitive function, are clearly contributing to human health and healthspan.

Not SupportedChicken and pork fed corn and soy have increased linoleic acid, making them less ideal than grass-fed red meat.

Partially SupportedThree grams of taurine per day for seven weeks decreased body weight, plasma triglycerides, and atherogenic index in overweight and obese adults.

Partially SupportedLong-term oral administration of taurine for 52 weeks effectively reduced stroke-like episode recurrence in MELAS syndrome patients.

Partially SupportedTaurine stimulates neurological development and acts as an inhibitory neurotransmitter in the central nervous system.

Partially SupportedMainstream views often associate red meat with poor longevity outcomes.

Partially SupportedUnique nutrients found in animal foods, specifically red meats and tendons, are beneficial for humans and have shown longevity benefits in mice, worms, and monkeys.

Partially SupportedCompounds found only in meat show astounding improvements in human trials and are likely more bioavailable from food sources.

Partially SupportedA 100g serving of beef cheek, heart, liver, or semitendinosis muscle contains between 42 and 452mg of carnosine.

Not SupportedThe hypothesis that meat is bad for longevity is based on misinterpreted epidemiology, exclusion of data, and ignorance of unique nutrients found in meat.

Partially SupportedAnserine and carnosine mixes can improve functioning in elderly subjects with alternate cognitive impairment, inhibit inflammatory cytokines, enhance muscular strength and exercise performance, ameliorate stress, enhance physiological strength, improve metabolic profiles, immunity, neurological function, wound healing, and promote lactation in females.

Partially SupportedBrian Johnson takes over 100 supplements daily, many of which are nutrients found abundantly in animal foods.

Partially SupportedAnserine at 10 or 100mg per 45kg body weight reduced blood glucose concentrations in elderly subjects.

Partially SupportedSome epidemiological studies do not show an association between red meat consumption and premature death or worsening cardiovascular disease, nor do they show benefits with vegetarian diets.

Partially SupportedRed meat should not be overcooked to preserve nutrients like taurine.

Partially SupportedCreatine is an inexpensive, safe dietary supplement with both muscular and neurological effects.

Partially SupportedDoses of carnosine, creatine, or taurine found in animal foods are reasonably attainable and sometimes slightly lower than studied doses.

Partially SupportedCarnosine at 0.5g to 2g per day for up to 6 months in patients with heart failure enhanced cardiac output and improved quality of life.

Partially SupportedLong-term daily supplementation with folic acid and vitamin B12 in elderly subjects affects DNA methylation.

Partially SupportedDeficiency in folate, B12, or B6 is frequently inadequate in the elderly and associated with cognitive decline.

Not SupportedRed meat contains essential nutrients like taurine, creatine, vitamin K2, vitamin B12, and vitamin B6, which may contradict claims that it is bad for longevity.

Not SupportedVegan diets are highly inferior if they do not include supplementation with nutrients exclusively found in meat.

Partially SupportedA mix of anserine and carnosine maintained adequate brain blood flow, preserved verbal episodic memory, and improved resting state network connectivity in elderly subjects.

Partially SupportedThe core principle of the animal-based diet is to understand which foods offer the most nutrients with the least plant toxins.

Partially SupportedProcessed red meats can contain preservatives like carrageenan, emulsifiers, and dyes, and may be derived from lower quality animals, unlike unprocessed ground beef from a butcher.

Partially SupportedCarnosine at 1g/day for 12 weeks improved metabolic profiles and decreased protein glycosylation and body fat in patients with type 2 diabetes.

Not SupportedA vegan diet requiring over 100 supplements to replicate red meat's nutrient profile is likely flawed.

Partially SupportedTaurine acts as a major antioxidant, is anti-inflammatory, and is a programmed cell death factor.

Partially SupportedTaurine is a physiological stabilizer of cell membranes, regulates calcium signaling and fluid homeostasis, supports retinal photoreceptor activity, contributes to osmoregulation, and is a key component of nerve and muscle conduction networks.

Partially SupportedOral administration of 2 grams of taurine per day for 4 weeks resulted in clinically significant reductions in the frequency, duration, and intensity of muscle cramps in patients with chronic liver disease.

Partially SupportedA 100g serving of semitendinosis muscle contains 36mg of taurine.

Partially SupportedThree grams of taurine per day for 30-45 days decreased left ventricular diastolic volume and increased serum creatinine in heart failure patients.

Partially SupportedTaurine protects cells and tissues from the toxicity of reactive oxygen species, excess metals, and ammonia.

Partially SupportedSupplementing with 1.5 to 2.5 grams of taurine per day for 12 weeks in children with retinal abnormalities improved retinal health.

Partially SupportedUS beef consumption declined from 95 lbs per person in 1976 to 60 lbs in 2017.

Partially SupportedSupplementation with carnosine and taurine is likely unnecessary for most people if they consume adequate animal-based protein.

Partially SupportedCarnosine, found only in meat, may enhance gastric healing in patients with gastric ulcers.

Partially SupportedProminent vegan athletes taking meat-exclusive supplements suggests red meat is beneficial for longevity.

Not SupportedRed meat is a health food and arguments against its longevity benefits are flawed.

Partially SupportedGrass-fed and grass-finished red meat is considered the cleanest and best source of nutrients within an animal-based diet.

Partially SupportedEx-vegans report feeling significantly better and experiencing positive effects on mood and well-being after adopting an animal-based diet and consuming beef organs.

Partially SupportedPaul Saladino and Brian Johnson have differing views on achieving longevity and healthspan.

Partially SupportedMultiple observational epidemiological studies show no benefit to avoiding meat in the human diet, and similar all-cause mortality rates between vegetarians and omnivores.

Partially SupportedPaul Saladino has previously released podcasts discussing meat and longevity and debunking vegan arguments related to longevity.

Partially SupportedCarnosine at 2g/day for 12 weeks improved metabolic profiles and increased lean tissue mass in humans.