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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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Heart Disease: Labs & Diagnostic Tests | Peter Attia, M.D. — Whalespan

Content›Video›Heart Disease: Labs & Diagno…

Heart Disease: Labs & Diagnostic Tests | Peter Attia, M.D.

Peter Attia6m · 2022-08-30

Claims Made

13

Claims Supported

10

Support Rate

77%

Support rate

10 of 13 claims supported

10 supported3 partial / not

Claims from this content

11

✓Well SupportedBy the late 30s or early 40s, any ApoB level above the 20th percentile (approximately 80 mg/dL) should be aggressively lowered.◐Partially SupportedA CT angiogram (CTA) with contrast provides detailed visualization of arteries, including soft plaque and luminal narrowing, and involves a radiation dose of approximately 2 millisieverts when performed well.◐Partially SupportedA coronary artery calcium score and a CT angiogram are the two most important diagnostic tests for assessing existing atherosclerosis.◐Partially SupportedBiomarkers can predict cardiovascular risk and are manageable through interventions.Partially Supported

More from Peter Attia

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Peter Attia on Rapamycin (with Matt Kaeberlein)

Attia walks back the clinic protocol: too aggressive for healthy adults

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A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

◐

A coronary artery calcium (CAC) score, obtained via a quick CT scan without contrast, measures calcification in coronary arteries and indicates a late stage of atherosclerosis.

◐Partially SupportedNon-HDL cholesterol should be monitored in addition to a standard lipid panel.

◐Partially SupportedA non-zero coronary artery calcium score indicates the presence of atherosclerosis.

◐Partially SupportedHomocysteine, uric acid, thyroid function, and iron/ferritin levels are monitored to manage cardiovascular risk.

◐Partially SupportedBlood pressure is aggressively monitored and treated with behavioral changes even for slight elevations.

◐Partially SupportedApolipoprotein B (apoB) and apolipoprotein E (apoE) are largely unrelated for cardiovascular risk assessment.

◐Partially SupportedThere is a distinction between predictors of cardiovascular risk and indicators of existing arterial damage.