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Weekly · Sunday Morning

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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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Linking autoimmunity and poor gut health — Whalespan

Content›Video›Linking autoimmunity and poo…

Linking autoimmunity and poor gut health

Paul Saladino9m · 2022-04-10

Claims Made

16

Claims Supported

8

Support Rate

50%

Support rate

8 of 16 claims supported

8 supported8 partial / not

Claims from this content

10

◐Partially SupportedGluten acts as a lectin and can trigger gut irritation and potential autoimmune responses in some individuals.◐Partially SupportedImmune cells attacking glial cells in multiple sclerosis and beta cells in type 1 diabetes may originate in the gut.◐Partially SupportedThe gut epithelium is a single layer of endothelial cells connected by junctional proteins like tight junctions and zonulin, separating the internal body from the external environment.◐Partially SupportedIndividuals without medical degrees can access and understand medical literature, such as PubMed, as effectively as doctors.Partially Supported

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AV

A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

◐

Food molecules may possess epitopes that resemble bacterial PAMPs or DAMPs, potentially triggering gut leakiness and initiating an immune response.

◐Partially SupportedUndigested food proteins passing through a compromised gut lining can activate immune cells, potentially leading to autoimmune responses.

◐Partially SupportedThe majority of the body's immune system cells are located in the lamina propria, a layer of the gut wall.

✕Not SupportedWestern healthcare's focus on specializing in downstream symptoms of metabolic dysfunction, rather than the underlying root cause, is a major blind spot contributing to worsening health outcomes.

◐Partially SupportedLeaky gut occurs when a trigger causes gut gap junctions to open, allowing immune cells to enter and proteins to potentially cross, leading to immune system overactivation.

◐Partially SupportedThe gut immune system increases gut permeability to react to pathogens like bacteria and parasites.