International Society of Sports Nutrition position stand: safety and efficacy of creatine supplementation in exercise, sport, and medicine

5g/day creatine monohydrate is safe and effective for strength and lean mass across 12+ RCTs, n>2,800.

• 01Design: Position statement — weighted accordingly in our rubric.
• 02Large or multi-site sample with low risk of bias.
• 03Effect direction is consistent with adjacent literature in our index.

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