Weekly rapamycin dosing in healthy adults: PEARL trial 48-week safety and immune markers

Weekly rapamycin shows acceptable safety in healthy adults over 48 weeks. Effect on aging markers preliminary.

• 01Design: Phase 2 RCT (humans) — weighted accordingly in our rubric.
• 02Solid design; some limitations on generalizability or duration.
• 03Effect direction is consistent with adjacent literature in our index.

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