How a Drug Gets Approved: Safety, Trials, and Funding | Susan Desmond-Hellmann M.D., M.P.H

Well SupportedBevacizumab combined with chemotherapy in stage 4 colon cancer resulted in approximately eight more months of median survival.

Partially SupportedPhase one clinical trials determine if a molecule is safe to administer to humans in single and multiple doses.

Partially SupportedPhase 2 trials can cost tens to tens of millions of dollars.

Partially SupportedPhase 2 clinical trials determine optimal dose and schedule, identify the correct patient population, and establish a hypothesis for Phase 3.