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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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Is It Too Late for Hormone Therapy After Menopause? | Rachel Rubin, M.D. — Whalespan

Content›Video›Is It Too Late for Hormone T…

Is It Too Late for Hormone Therapy After Menopause? | Rachel Rubin, M.D.

Peter Attia3m · 2025-05-16

Claims Made

7

Claims Supported

5

Support Rate

71%

Support rate

5 of 7 claims supported

5 supported2 partial / not

Claims from this content

7

✓Well SupportedVaginal estrogen or DHEA can substantially reduce the risk of urinary tract infections (UTIs).◐Partially SupportedHormone therapy is indicated for vasomotor symptoms, prevention of osteoporosis, and the genital and urinary syndrome of menopause.✕Not SupportedStopping hormone therapy without a specific medical reason may disrupt existing plaques and cause vasospasms in women.◐Partially SupportedStopping hormone therapy after 10 years causes bone gains to disappear quickly.◐Partially Supported

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Attia walks back the clinic protocol: too aggressive for healthy adults

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AV

A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

The only valid reason to stop hormone therapy is if a woman has an active cancer that is targeted by hormone treatment.

✕Not SupportedThe strategy of using hormone therapy for the shortest duration and lowest dose, and stopping after 10 years, is not supported by data.

◐Partially SupportedWithholding hormone therapy in women who undergo surgical menopause without cancer can shorten lifespan due to negative impacts on bone health and cardiovascular disease.