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Benefits hold across the populations where it's been tested.
The effect size is large enough to matter clinically, not just statistically.
The effect size is large enough to matter clinically, not just statistically.
The effect size is large enough to matter clinically, not just statistically.
Mechanistic and trial evidence converge on a real, replicable effect.
Most of the support comes from short or small studies.
Confounding and publication bias inflate the apparent benefit.
Confounding and publication bias inflate the apparent benefit.
The headline effect shrinks once you account for trial quality.
The headline effect shrinks once you account for trial quality.