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Mechanistic and trial evidence converge on a real, replicable effect.
Mechanistic and trial evidence converge on a real, replicable effect.
Benefits hold across the populations where it's been tested.
Benefits hold across the populations where it's been tested.
Mechanistic and trial evidence converge on a real, replicable effect.
Most of the support comes from short or small studies.
Confounding and publication bias inflate the apparent benefit.
Confounding and publication bias inflate the apparent benefit.
Confounding and publication bias inflate the apparent benefit.
Animal-model results don't translate to the human protocol being recommended.