David Sinclair· PhD
FDA drugs that may slow aging are acarbose, rapamycin and metformin.
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
FDA drugs that may slow aging are acarbose, rapamycin and metformin.
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
Acarbose is available by prescription here in US, like metformin, the other diabetes drug that may delay aging
I would put canagliflozin ahead of it, though. Not only was it successful in the ITP, but the human data is more impressive.
since a carbos is fda approved and has a long safety history hundreds of thousands of people take it particularly in asia and in some parts of europe it's an obvious candidate for a human clinical trial the safety profile is is quite good it's very well documented with many cases having been evaluated for safety so if one was thinking about what drug that works pretty well in mice would be safe for a human clinical trial a carbos has to be on that list