Andrew Huberman· PhD
you know some East Asians have a mutation that leads to Flushing um and so that may put those men at higher risk when they mix alcohol we may see some you know slightly lower uh sperm parameters
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
you know some East Asians have a mutation that leads to Flushing um and so that may put those men at higher risk when they mix alcohol we may see some you know slightly lower uh sperm parameters
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although a faster metabolism of ethanol into acetylide is associated with having less severe hangover symptoms there's no evidence that a faster elimination of acety alahh which hangover products like zbiotics claim to promote is effective for reducing hangover severity
some people who possess an alternative form of a gene known as aldah dehydrogenase 2 which make them makes them slower at metabolizing acetyl alahh report experiencing worse hangover symptoms and experien hangovers at a lower level of alcohol consumption which is some indirect evidence that modifying the activity of acety alide metabolizing enzymes could affect hangover symptom severity