Rhonda Patrick· PhD
LPS is harmless inside the intestine, but in the circulation, it’s highly toxic and induces an inflammatory response throughout the body and the brain.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
LPS is harmless inside the intestine, but in the circulation, it’s highly toxic and induces an inflammatory response throughout the body and the brain.
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When LPS enters the bloodstream, it's linked to: • Type 2 diabetes • Heart disease • And liver disease
One of the most well-known of these so-called endotoxins is known as lipopolysaccharide or LPS LPS provides a structural barrier to bacterial cells and is normally only present in the luminal or inner side of our intestinal cells where it doesn't cause damage but if LPS is able to cross the intestinal barrier through some sort of mechanisms we just discussed it can enter the bloodstream where it's highly toxic and has been linked to type 2 diabetes heart disease and liver disease LPS in the bloodstream induces an inflammatory response increasing the levels of cyto kindes including tnf Alpha Incan 6 and the chemokine mcp1