Paul Saladino· MD
alcohol is known to create intestinal inflammation including altering intestinal microbiotic composition and function increasing the permeability of the intestinal lining affecting the intestinal immune homeostasis
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
alcohol is known to create intestinal inflammation including altering intestinal microbiotic composition and function increasing the permeability of the intestinal lining affecting the intestinal immune homeostasis
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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because alcohol's main negative effects are through causing a leaky gut and increasing the influx of endotoxin to the liver and so I think that the parallels you're seeing there are more again a function of the endotoxin
Alcohol directly interferes with micronutrient absorption by causing structural damage to the intestinal lining, disrupting gut microbiome composition, and increasing intestinal permeability, also known as “leaky gut.”
Micronutrient deficiencies may be one explanation for why heavy alcohol consumption is linked to a variety of diseases, and this is probably not something that can be avoided by simply taking a micronutrient supplement to compensate.