Estimating the age of individual cell types, such as brain astrocytes, is more predictive of Alzheimer's than assessing whole organ age.

“So here we have now a a much finer resolution and granularity where we can get more predictive power. We can get more precise prediction of what type of disease you might get. And of course at the molecular level and the cellular level we we know where the problem might be right it's not just the whole organ but now we know which cell type. Another one was there's these cells we call aststerytes in the brain. We find a very strong association of the age of aststerytes and development of Alzheimer's disease much stronger than just the brain age.”