Depletion of dopamine neurons in specific brain locations causes Parkinson's disease and Louis body dementia symptoms.

“in diseases like Parkinson's or Louis body's dementia which is similar to Parkinson's in many ways there's a depletion or death of dopamine neurons at a particular location in the brain which leads to shaky movements challenges in speaking challenges in particular in initiating movement and because dopamine is depleted elsewhere too people with Parkinson's and Louis and excuse me Louisibody dementia also experience drops in motivation and affect meaning mood they tend to get depressed and so on.”