Peter Attia· MD
there is now quite a lot of observational data that strongly suggests that apoa1 is protective against neurodegenerative disease
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
there is now quite a lot of observational data that strongly suggests that apoa1 is protective against neurodegenerative disease
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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the association of plasma apoa1 and HCL cholesterol with neurodegenerative diseases such as Dementia or Alzheimer's disease
so the plausibility of April A1 being protective against neurodegenerative disease particularly Alzheimer's is quite high and frankly there's a lot of work to be done to try to figure it out