David Sinclair· PhD
We can reverse the age of a brain in an animal, and when we do that, we're showing, and we will continue to test this, that those diseases go away, proving that those diseases are actually caused by aging.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
We can reverse the age of a brain in an animal, and when we do that, we're showing, and we will continue to test this, that those diseases go away, proving that those diseases are actually caused by aging.
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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And it's my belief in my labs, evidence that if you reverse the age of the human brain, Alzheimer's and other diseases of the brain will go away, and you'll even get your lost memories back again.
So this is the beginnings of work that I hope will mean that we can reverse the age of the brain and other tissues, and diseases of old age, like Alzheimer's, heart disease, even cancer, will go away.