Consistent overthinking, worrying, or considering worst-case scenarios, especially at night, may indicate a COMT gene mutation.

“most of the expression in comp te is a waking mind at night or consistent overthinking worrying um um you know laying down and constantly considering worst case scenario if you know somebody who is um constantly just goes to the worst case scenario who lays down to go to bed at night and their environment quiets but their mind wakes up um they constantly overthinking things and um this is indicative of not always but it's indicative of of of comp team mutation”