Statins affect the HMG-CoA pathway, impacting cholesterol synthesis and ubiquinol (CoQ10) synthesis, which is crucial for mitochondrial function.

“so statins are affecting the HMG co co pathway that you mentioned the cholesterol synthesis with which also is important for the synthesis of uh ubiquinol right this is an important or coq1 as I should probably call it um this is important for mitochondrial function I mean it's necessary for mitochondrial function for transferring electron electrons across the electron transport chain which is essentially coupling the oxygen we breathe with the food that we eat to make energy”