Bryan Johnson· Author
As age increases, bleeding risk, including gastrointestinal and intracranial hemorrhage, rises substantially, further worsening the risk–benefit balance and making aspirin progressively less favorable for primary prevention.
We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
As age increases, bleeding risk, including gastrointestinal and intracranial hemorrhage, rises substantially, further worsening the risk–benefit balance and making aspirin progressively less favorable for primary prevention.
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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in make sure that people over the age of seventy who took aspirin for primary prevention actually had increased mortality rates