Berberine is a non-prescription compound that mimics the actions of Metformin and activates the AMPK pathway.

“which by the way is very much like Metformin, its effects are almost identical to Metformin in fact, but it's much less expensive and it's over the counter.”

“berberine is a plant derived extract that has two properties one of which it gets a lot of attention for one of which it might not be as well known the first is that it is a weak a MP kinase activator and for those of you that have you know shown an interest in what metformin does that's sort of the the that's probably the secret sauce of metformin is its ampk activation so berberine when taken at you know sort of recommended OTC doses which I remember the doses anymore I think it's like a it might be actually a comparable dose to metformin it might be like either 500 twice a day or a thousand twice a day does have some of that weak AMPK activation”

“berberine is a plant derived extract that has two properties one of which it gets a lot of attention for one of which it might not be as well known the first is that it is a weak am p kinase activator and for those of you that have shown an interest in what metformin does that's sort of the the that's probably the secret sauce of metformin is its ampk activation”