Fluorescent-based methods using DNA-binding dyes are a common, fast, and simple way to quantify cell-free DNA concentration in plasma.

“the most commonly used one in our lab is a fluorescent-based method where you basically add a fluorescent dye to to the solution it binds to dna and that gives a specific fluorescence and then you can read that out in a in a machine that can read that fluorescence so you can then have this and have a standard curve and read off how much dna you have”