Cancer genomes typically have around 100 mutations in coding regions and tens of thousands in the whole genome.

“a cancer the cancer is only going to have maybe a hundred mutations yeah so a hundred mutation in the coding regions exactly that's right in the coding regions in the total genome if you include the the regions between genes may be you know 10 to 20 000 or something it depends of course as a range but no more than ten having more than tens of thousands of mutations in the whole genome would be unusual”