GDF-15 is a key biomarker for mitochondrial disease, elevated when mitochondria signal distress.

“GDF-15 goes through the roof so now people know in cardiology GDF-15 is a really good marker of heart failure and then the the thinking I think our way of thinking energetically about GDF-15 is a little different than what the rest of I think the the field thinks people see GDF 15 as a marker of inflammation And then maybe that's like immune or I think it's it's a marker of energetic stress. The heart is calling out for help and trying to kind of calm down the rest of the system, right? By signaling onto the brain.”