Bryan Johnson· Author
measure your S-100B levels (via blood draw).
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
measure your S-100B levels (via blood draw).
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If it’s elevated you’re experiencing brain damage.
So, just like you mentioned, Kate, S100B is um associated with uh brain injury. And the reason for that is because it's um it's more closely associated with um cell repair and signaling within the brain and is often um found to be elevated when there's a damage to the protective layer around the brain. Uh most specifically what's called the bloodb brain barrier. And that's been associated with concussions, traumatic brain injury, brain swelling, uh and even sleep disruption. Um, so the fact that there was this elevation in this S100B protein, while it doesn't say that there's definitely brain damage, it's often used in clinical trials as a surrogate to subclinical brain damage, meaning brain damage that where we don't see outward signs yet.