A specific breathing protocol involving repeated cycles of deep inhales and exhales followed by breath holds reduced symptoms when participants were injected with endotoxin.

“And they discovered that levels of proinflammatory TNF-alpha, tumor necrosis factor alpha, IL-6, interleukin-6 and interleukin-8, which you should all be familiar with now, as proinflammatory cytokines were lower in the intervention group. Whereas these IL-10 levels that are anti-inflammatory went up.”

“the way the experiment went is that people were injected with endotoxin or in some cases they were injected with with a bacterial wall that mimics infection it g it gives you a fever it makes you feel nauseous it makes you feel sick it is not pleasant Half of the people did a particular pattern of breathing that looked very much like the pattern of breathing I described a moment ago of doing 25 deep inhales and exhales followed by an exhale holding their breath then repeating 25 inhales exhales holding their breath so this would look something like this or if you're listening it sounds like 25 30 times you'll start feeling heated up you'll start feeling the adrenaline response you're liberating adrenaline in your body then exhale hold your breath for 15 seconds and then repeat”