Paul Saladino· MD
guys caffeine ingestion before an oral glucose tolerance test impairs blood glucose management in men with type 2 diabetes guess what caffeine worsens insulin sensitivity metabolic and hormonal effects of caffeine randomized double-blind placebo-controlled crossover trial shows that insulin levels were significantly higher which means more insulin resistance after caffeine intake relative to placebo the homa ir index of insulin sensitivity was reduced by 35 percent that is worsening insulin sensitivity by caffeine so again this is showing caffeine worsens insulin sensitivity systematic review of randomized controlled trials of the effects of caffeine and caffeinated drinks on blood glucose concentrations and insulin sensitivity to people with diabetes mellitus evidence indicates a negative effect of caffeine intake on blood glucose control individuals type 2 diabetes as replicated in a single trial in gestational diabetes