Andrew Huberman· PhD
what they showed was that caffeine can increase dopamine release in the brain by about 30%. That wasn't surprising. I even said that earlier, but what they also showed is that it has a protective effect on dopamine neurons.
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
what they showed was that caffeine can increase dopamine release in the brain by about 30%. That wasn't surprising. I even said that earlier, but what they also showed is that it has a protective effect on dopamine neurons.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
But if one were going to consume caffeine, you might consider consuming that caffeine in the form of yerba mate both for sake of upregulating dopamine receptors and getting more of a dopamine increase.
Yerba mate turns out has also been shown to be neuroprotective specifically for dopaminergic neurons.
It also contains something called GLP-1, which is favorable for management of blood sugar levels. Yerba mate, it turns out, has also been shown to be neuroprotective specifically for dopamineergic neurons. Ingestion of yerba mate and some of the compounds within yerba mate can actually serve to preserve the survival of dopamine neurons in both the movement related pathway and the motivation pathway.
If one were going to consume caffeine, you might consider consuming that caffeine in the form of yerba mate. Both for sake of upregulating dopamine receptors and getting more of a dopamine increase and of course for the stimulate properties of caffeine if that's what you're seeking and in addition to that because yerba mate does appear to have some sort of neuroprotective and in particular dopamine neuron protective properties.