Andrew Huberman· PhD
a partial response is at least a 50% reduction by diameter because remember in this type Imaging you're looking at 2D versus 3D so if you're looking at a lung lesion and it's this big it you know if it's 2 centimeters long it has to go to at least 1 centimeter in diameter so it's a 50% reduction at least of every single lesion with no new lesions appearing and no lesions growing so it's very strict criteria right again CR means everything vanishes PR means at least a 50% by diameter which by the way is a much bigger diameter much bigger reduction in terms of tumor volume when you consider the linear versus the third power relationship of length and volume of every single lesion with nothing new appearing regardless of how small and no lesion growing so that's a PR