Andrew Huberman· PhD
there is another receptor on the t- cell a ctla4 receptor and that binds to a receptor that I won't bother naming now because it's the the the names don't matter but there's another receptor on the antigen presenting cell that binds to that and that acts as the breaks in the reaction so ctla4 which is on the t- cell binds to another CD receptor on the antigen presenting cell and it says Tamp down the response and the reason for that is we want to keep our immune system in check this basically is a way of asking the immune system because remember when the immune system sees that antigen it wants to go nuts it wants to start replicating and killing that this is a cd8 cell it is a targeted killer t- cell the checkpoint says let's double check that let's be sure let's Tamp down the response