Activating PPAR-alpha pushes linoleic acid down a pathway that results in oxylipins, which are signaling molecules associated with heart disease, diabetes, and obesity.

“when something triggers this enzyme called PP alpha peroxone proliferator alpha it pushes linolic acid the 18 carbon polyant fat found in seed oils down a synthesis pathway that ends up in all of these Ox Lambs so what activates PPA are alpha we've talked about alic acid oxidized linolic acid alpha linolenic acid and other things do as well but those are those are big ones not regular linolic acid doesn't do it but alic acid does so if you end up with a seed oil like canola oil that has a lot of OIC acid plus linolic acid plus ala alpha linolenic acid an omega-3 plus an Omega 6 plus a monounsaturated fat you basically push a lot of things down this pathway linolic acid becomes arachadonic acid through GLA dlaa and then it becomes the Heats and Hodes and all of these Ox lams that I've talked about in the past people like Tucker good rich and these are strongly associated with many many bad diseases in humans heart disease diabetes obesity 5 and 11 heat associated with obesity in humans”